Topic:

Personalized Medicine

Latest Headlines

Latest Headlines

Brain scan may provide biomarker guideposts to ideal depression treatment

Activity in certain parts of the brain appears to offer solid biomarker guideposts to whether drugs or psychotherapy works best to treat depression, researchers have found. And a pretreatment brain scan helps make the determination.

UPDATED: In mixed decision, Supreme Court throws up a barrier around gene patents

In a mixed decision, the Supreme Court has ruled that companies can not obtain a patent on human genes. But companies like Myriad Genetics will be able to nail down patent protection on complementary gene work, or cDNA, which requires human tinkering.

Quintiles: Patient selection, biomarkers key to cancer R&D

As the top cancer researchers gather in Chicago, the world's largest CRO is weighing in on how best to steer the future of oncology drug development, arguing that picking the right patients and biomarkers in early stages can mean the difference between a blockbuster and a late-phase failure.

UPDATED: GlaxoSmithKline gains FDA OK on two genetically targeted melanoma drugs

In an important win for GlaxoSmithKline's R&D division, the FDA today announced that it has approved a pair of genetically targeted melanoma drugs, dabrafenib and trametinib, from the company, along with a diagnostic test that can be used to identify the patients most likely to respond to the treatments.

New CTC technology looks promising to track evolution of prostate cancer

Researchers in California say they believe circulating tumor cells, captured and analyzed by new technology, could function as a 'liquid biopsy." If further studies confirm the effectiveness of the NanoVelcro Chip, prostate cancer could be more easily tracked over time to provide personalized treatments.

Swedish team discovers protein common to aggressive bladder cancer

Swedish researchers believe that screening for the biomarker, perhaps with a simple urine test, could allow for more targeted treatment at an earlier enough stage to give patients a fighting chance, or at least indentify realistic options.

Cenix to collaborate with Debiopharm on predictive biomarkers

The preclinical CRO Cenix BioScience has struck a deal to work with Germany's Debiopharm, putting its experts to work finding predictive biomarkers that can be used to advance the biotech's cancer drug candidates.

Stabilizing a gene reverses schizophrenia in mice

Scientists at Georgia Regents University may have discovered the key to reversing schizophrenia, a complex disorder that affects about 1% of the U.S. population.

Drug boosts effectiveness of radiation therapy for brain tumors

An enzyme inhibitor that helps repair DNA damage may provide a new way to boost the effectiveness of radiation therapy for a lethal type of brain cancer.

Bristol-Myers Squibb pursues cancer biomarker development deal

Bristol-Myers Squibb will collaborate with Adaptive Biotechnologies to develop immunological biomarkers for cancer, representing another step forward in the development of personalized medicine.