GlaxoSmithKline is broadening its reach in the big U.S. R&D field in coming months, ramping up satellite innovation centers in Cambridge, MA, and San Diego where its teams can shepherd a growing flock of research partnerships while hunting down new technologies and spawning biotech startups.
Morrisville, NC-based Gentris is setting up a new genomic biomarker testing service in Shanghai, a growing global hub for drug development.
A new study out of UCLA points to a potential biomarker for identifying which patients have the "fast" form of the disease and will need significant help early on.
After earlier this month announcing promising new data supporting its genetic treatment for hepatitis B, Arrowhead Research is moving forward with the candidate, submitting its application to begin a Phase IIa trial of ARC-520, which uses its polymer-based method to effectively deliver RNAi to the nucleus.
Regulus Therapeutics has partnered up with Biogen Idec to identify microRNA biomarkers in the blood of patients with multiple sclerosis, and the California biotech has charted some progress, pocketing a milestone payment and moving toward companion diagnostic development.
Gene-silencing expert Alnylam is $7 million richer thanks to some positive mid-stage results for its Genzyme-licensed RNA-interference candidate, and the Cambridge, MA, company is looking to be the first to market with the difficult-to-deliver class of treatments.
An investigative team at the University of Zurich says they have nailed down some clear proof-of-principle evidence in animal studies that a combination of interleukin-12 used in a combo immunotherapy approach offers a promising new avenue of research in tackling lethal cases of brain cancer.
AstraZeneca hammered the local economy in Loughborough, U.K., in 2011 when it closed down a 70-acre research campus and ditched 1,200 jobs in the process. Now developers are working to pick up the pieces, rebranding the drug development ghost town with hopes of luring new tenants while Big Pharma moves away from the model of secluded R&D.
Researchers in Finland have come up with a new application for well-known materials known as bisphosphonates that includes a possible role for drug delivery.
Merrimack Pharmaceuticals and its partners at Sanofi are back with another trial failure to report on the biotech's lead drug, MM-121. Combined with exemestane, the drug failed to improve progression-free survival among a group of ER/PR+, HER2 negative breast cancer patients.